Anti-TOP2B Antibody
Cat. No.
Y058353
Unit
100 μl
Price
$152.00
Specifications
| Cat. No. | Y058353 |
| Name | Anti-TOP2B Antibody |
| Clone | Polyclonal |
| Price | $152.00 |
| Unit | 100 μl |
| Category | Polyclonal Antibodies |
| Gene Name | TOP2B |
| Application | IHC,ELISA |
| Application Info | For research use only Peptide ELISA titer: 1:1,000-1:10,000 Immunohistochemistry: 1:50-200 Optimal dilutions/concentrations should be determined by the end use. |
| Raised In | Rabbit |
| Clonality | Polyclonal |
| Reactivity | Human |
| Description | This gene encodes a DNA topoisomerase, an enzyme that controls and alters the topologic states of DNA during transcription. This nuclear enzyme is involved in processes such as chromosome condensation, chromatid separation, and the relief of torsional stress that occurs during DNA transcription and replication. It catalyzes the transient breaking and rejoining of two strands of duplex DNA which allows the strands to pass through one another, thus altering the topology of DNA. Two forms of this enzyme exist as likely products of a gene duplication event. The gene encoding this form, beta, is localized to chromosome 3 and the alpha form is localized to chromosome 17. The gene encoding this enzyme functions as the target for several anticancer agents and a variety of mutations in this gene have been associated with the development of drug resistance. Reduced activity of this enzyme may also play a role in ataxia-telangiectasia. Alternative splicing of this gene results in two transcript variants; however, the second variant has not yet been fully described. [provided by RefSeq, Jul 2008] |
| Immunogen | Rabbit polyclonal TOP2B antibody was raised against a 15 amino acid peptide from near the C terminal residues of human TOP2B. |
| Isotype | IgG |
| Concentration | 100ug/100ul |
| Recommended Dilutions | For research use only Peptide ELISA titer: 1:1,000-1:10,000 Immunohistochemistry: 1:50-200 Optimal dilutions/concentrations should be determined by the end use. |
| Storage Buffer | PBS, pH 7.4 with 0.02% Sodium Azide |
| Storage Condition | This product is stable for several weeks at 4°C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20°C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt. |
| Formulation | Liquid |
| Species Reactivity | Human |
| Purity | Affinity purified |
| Guarantee | abm guarantees that all our Anti-TOP2B Antibody will perform as described on this product webpage, if this is not the case we will provide you with a one-time replacement at no extra cost. Documentation and explanation of experiment conducted will be required when submitting a claim for replacement. |
| Depositor | SaierBio |
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