Anti-Synphilin-1 (829-847) Antibody
Cat. No.
Y075043
Unit
100 μl
Price
$560.00
Specifications
| Cat. No. | Y075043 |
| Name | Anti-Synphilin-1 (829-847) Antibody |
| Price | $560.00 |
| Unit | 100 μl |
| Category | Polyclonal Antibodies |
| Gene Name | Synphilin-1 |
| Application | IHC |
| Application Info | A dilution of 1: 1000 to 1:2000 is recommended for this application. The optimal dilution should be determined by the end user. This antiserum will stain Lewy bodies in Dorsal raphe nucleus of Parkinson's diseased human brain. |
| Raised In | Rabbit |
| Clonality | Polyclonal |
| Reactivity | Human,Rat |
| Description | Synuclein alpha interacting protein (Synphilin-1) contains several protein-protein interaction domains and interacts with alpha synuclein in neurons. Mutations of SNCAIP have been linked to Parkinson disease. The amino acid sequence of synphilin-1 shares a high level of identity with its human counterpart, particularly in regions containing ankyrin-like motifs and the coiled-coil domain. Expression pattern of synphilin-1 in tissues is similar in both mouse and human. Synphilin-1 has an important role in the formation of aggregates and cytotoxicity in Parkinson disease and also Dorfin may be involved in the pathogenic process by ubiquitylation of synphilin-1. |
| Immunogen | A synthetic peptide (SLELNGEKDKDKGRTLQRT) as part of human synphilin-1a conjugated to KLH has been used as the immunogen. |
| Concentration | 1ug/ul |
| Recommended Dilutions | A dilution of 1: 1000 to 1:2000 is recommended for this application. The optimal dilution should be determined by the end user. This antiserum will stain Lewy bodies in Dorsal raphe nucleus of Parkinson's diseased human brain. |
| Storage Buffer | PBS, pH 7.4 with 0.02% sodium azide. |
| Storage Condition | This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20° C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt. |
| Formulation | Liquid |
| Species Reactivity | Human,Rat |
| Specificity | A high level of specificity has been shown for this antiserum by IHC on human brain. |
| Purity | Filter purified |
| Guarantee | abm guarantees that all our Anti-Synphilin-1 (829-847) Antibody will perform as described on this product webpage, if this is not the case we will provide you with a one-time replacement at no extra cost. Documentation and explanation of experiment conducted will be required when submitting a claim for replacement. |
| Depositor | Biosensis |
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