Anti-SRY (Mouse Monoclonal) Antibody
Cat. No.
G052
Unit
100 μg
Price
$236.00
Specifications
| Cat. No. | G052 |
| Name | Anti-SRY (Mouse Monoclonal) Antibody |
| Clone | SRY.G12 |
| Price | $236.00 |
| Unit | 100 μg |
| Category | Monoclonal Antibodies |
| Application | WB,ELISA |
| Raised In | Mouse |
| Clonality | Monoclonal |
| Reactivity | Human |
| Description | This intronless gene encodes a transcription factor that is a member of the high mobility group (HMG)-box family of DNA-binding proteins. This protein is the testis-determining factor (TDF), which initiates male sex determination. Mutations in this gene give rise to XY females with gonadal dysgenesis (Swyer syndrome); translocation of part of the Y chromosome containing this gene to the X chromosome causes XX male syndrome. [provided by RefSeq, Jul 2008] |
| Immunogen | SRY-GST fusion protein. |
| Isotype | IgG |
| Concentration | 100ug/100ul |
| Recommended Dilutions | Western blot (1:1000) and ELISA (1:2000~5000). The Sex-Determining Region (SRY) is a gene that encodes a transcription factor that is a member of the high mobility group HMG-box family of DNA binding proteins.The gene is located on the short arm of the Y chromosome and has a gene map locus - Yp11.3.Common synonyms of the gene name are Testis Determining Factor (TDF) and Testis Determining Factor on Y (TDY). The main function of the SRY protein is to initiate male sex determination as a transcriptional activator, which regulates a genetic switch in male development. The SRY HMG box recognizes DNA by partial intercalation in the minor groove. The SRY protein then binds to the DNA and distorts its shape (SRY protein in action). In doing so, it regulates genes that control the development of the testes. |
| Storage Buffer | PBS, pH 7.4 with 0.05% sodium azide. |
| Storage Condition | This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20° C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt. |
| Formulation | Liquid |
| Specificity | Recognize mouse SRY protein, others not tested. |
| Guarantee | abm guarantees that all our Anti-SRY (Mouse Monoclonal) Antibody will perform as described on this product webpage, if this is not the case we will provide you with a one-time replacement at no extra cost. Documentation and explanation of experiment conducted will be required when submitting a claim for replacement. |
| Depositor | ABM |
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