Anti-Smad7 Antibody
Specifications
Cat. No. | Y058362 |
Name | Anti-Smad7 Antibody |
Clone | Polyclonal |
Price | $152.00 |
Unit | 100 μl |
Category | Polyclonal Antibodies |
Gene Name | smad7 |
Application | WB,IHC,ELISA |
Application Info | For research use only Peptide ELISA titer: 1:5,000-1:20,000 Western blot analysis: 1:500-1:1000 Immunohistochemistry: 1:50-200 Optimal dilutions/concentrations should be determined by the end use. |
Raised In | Rabbit |
Clonality | Polyclonal |
Reactivity | Human,Mouse,Rat |
Description | The protein encoded by this gene is a nuclear protein that binds the E3 ubiquitin ligase SMURF2. Upon binding, this complex translocates to the cytoplasm, where it interacts with TGF-beta receptor type-1 (TGFBR1), leading to the degradation of both the encoded protein and TGFBR1. Expression of this gene is induced by TGFBR1. Variations in this gene are a cause of susceptibility to colorectal cancer type 3 (CRCS3). Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2010] |
Immunogen | Rabbit polyclonal Smad7 antibody was raised against a peptide near intermediate residues of human Smad7 protein. |
Isotype | IgG |
Concentration | 100ug/100ul |
Recommended Dilutions | For research use only Peptide ELISA titer: 1:5,000-1:20,000 Western blot analysis: 1:500-1:1000 Immunohistochemistry: 1:50-200 Optimal dilutions/concentrations should be determined by the end use. |
Storage Buffer | PBS, pH 7.4 with 0.02% Sodium Azide |
Storage Condition | This product is stable for several weeks at 4°C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20°C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt. |
Formulation | Liquid |
Species Reactivity | Human,Mouse,Rat |
Purity | Affinity purified |
Guarantee | abm guarantees that all our Anti-Smad7 Antibody will perform as described on this product webpage, if this is not the case we will provide you with a one-time replacement at no extra cost. Documentation and explanation of experiment conducted will be required when submitting a claim for replacement. |
Depositor | SaierBio |
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