Anti-SMAD1 Antibody
Cat. No.
Y058305
Unit
100 μl
Price
$152.00
Specifications
Cat. No. Y058305
Name Anti-SMAD1 Antibody
Clone Polyclonal
Price $152.00
Unit 100 μl
Category Polyclonal Antibodies
Gene Name SMAD1
Alias MADR1, JV4-1
Application WB,IHC,ELISA
Application Info For research use only Peptide ELISA titer: 1:1000-1:10000 Western blot analysis: 1:200-1:1000 Immunohistochemistry: 1:200-500 Optimal dilutions/concentrations should be determined by the end use.
Raised In Rabbit
Clonality Polyclonal
Reactivity Human,Mouse,Rat
Description The protein encoded by this gene belongs to the SMAD, a family of proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein mediates the signals of the bone morphogenetic proteins (BMPs), which are involved in a range of biological activities including cell growth, apoptosis, morphogenesis, development and immune responses. In response to BMP ligands, this protein can be phosphorylated and activated by the BMP receptor kinase. The phosphorylated form of this protein forms a complex with SMAD4, which is important for its function in the transcription regulation. This protein is a target for SMAD-specific E3 ubiquitin ligases, such as SMURF1 and SMURF2, and undergoes ubiquitination and proteasome-mediated degradation. Alternatively spliced transcript variants encoding the same protein have been observed. [provided by RefSeq, Jul 2008]
Immunogen Rabbit polyclonal SMAD1 antibody was raised against a peptide from the C terminal residues of human SMAD1 protein.
Isotype IgG
Concentration 100ug/100ul
Recommended Dilutions For research use only Peptide ELISA titer: 1:1000-1:10000 Western blot analysis: 1:200-1:1000 Immunohistochemistry: 1:200-500 Optimal dilutions/concentrations should be determined by the end use.
Storage Buffer PBS, pH 7.4 with 0.02% Sodium Azide
Storage Condition This product is stable for several weeks at 4°C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20°C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt.
Formulation Liquid
Species Reactivity Human,Mouse,Rat
Purity Affinity purified
Guarantee abm guarantees that all our Anti-SMAD1 Antibody will perform as described on this product webpage, if this is not the case we will provide you with a one-time replacement at no extra cost. Documentation and explanation of experiment conducted will be required when submitting a claim for replacement.
Depositor SaierBio
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