Anti-RAD17 Antibody
Specifications
Cat. No. | Y058158 |
Name | Anti-RAD17 Antibody |
Clone | Polyclonal |
Price | $152.00 |
Unit | 100 μl |
Category | Polyclonal Antibodies |
Gene Name | RAD17 |
Alias | Rad24, RAD17Sp, CCYC |
Application | WB,ELISA |
Application Info | For research use only Peptide ELISA titer:1:80,000 Western blot analysis: 1:200-1000 Optimal dilutions/concentrations should be determined by the end use. |
Raised In | Rabbit |
Clonality | Polyclonal |
Reactivity | Human |
Description | The protein encoded by this gene is highly similar to the gene product of Schizosaccharomyces pombe rad17, a cell cycle checkpoint gene required for cell cycle arrest and DNA damage repair in response to DNA damage. This protein shares strong similarity with DNA replication factor C (RFC), and can form a complex with RFCs. This protein binds to chromatin prior to DNA damage and is phosphorylated by the checkpoint kinase ATR following damage. This protein recruits the RAD1-RAD9-HUS1 checkpoint protein complex onto chromatin after DNA damage, which may be required for its phosphorylation. The phosphorylation of this protein is required for the DNA-damage-induced cell cycle G2 arrest, and is thought to be a critical early event during checkpoint signaling in DNA-damaged cells. Eight alternatively spliced transcript variants of this gene, which encode four distinct proteins, have been reported. Two pseudogenes, located on chromosomes 7 and 13, have been identified. |
Immunogen | Synthetic peptide conjugated to KLH |
Isotype | Rabbit IgG |
Concentration | 100ug/100ul |
Recommended Dilutions | For research use only Peptide ELISA titer:1:80,000 Western blot analysis: 1:200-1000 Optimal dilutions/concentrations should be determined by the end use. |
Storage Buffer | PBS, pH 7.4 with 0.02% Sodium Azide |
Storage Condition | This product is stable for several weeks at 4°C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20°C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt. |
Formulation | Liquid |
Species Reactivity | Human |
Specificity | Not yet tested in other species. |
Purity | purified |
Guarantee | abm guarantees that all our Anti-RAD17 Antibody will perform as described on this product webpage, if this is not the case we will provide you with a one-time replacement at no extra cost. Documentation and explanation of experiment conducted will be required when submitting a claim for replacement. |
Depositor | SaierBio |
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