Anti-PPARD Antibody
Cat. No.
Y158480
Unit
100 μl
Price
$152.00
Specifications
| Cat. No. | Y158480 |
| Name | Anti-PPARD Antibody |
| Clone | Polyclonal |
| Price | $152.00 |
| Unit | 100 μl |
| Category | Polyclonal Antibodies |
| Gene Name | PPARD |
| Alias | NUC1, NUCII, FAAR, NR1C2 |
| Application | WB,IHC,ELISA |
| Raised In | Rabbit |
| Clonality | Polyclonal |
| Reactivity | Human,Mouse,Rat |
| Description | This gene encodes a member of the peroxisome proliferator-activated receptor (PPAR) family. PPARs are nuclear hormone receptors that bind peroxisome proliferators and control the size and number of peroxisomes produced by cells. PPARs mediate a variety of biological processes, and may be involved in the development of several chronic diseases, including diabetes, obesity, atherosclerosis, and cancer. This protein is a potent inhibitor of ligand-induced transcription activity of PPAR alpha and PPAR gamma. It may function as an integrator of transcription repression and nuclear receptor signaling. The expression of this gene is found to be elevated in colorectal cancer cells. The elevated expression can be repressed by adenomatosis polyposis coli (APC), a tumor suppressor protein related to APC/beta-catenin signaling pathway. Knockout studies in mice suggested the role of this protein in myelination of the corpus callosum, lipid metabolism, and epidermal cell proliferation. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jan 2010] |
| Immunogen | Rabbit polyclonal PPARD (1) antibody was raised against a recombinate human PPARD protein 19-90aa (BC002715). |
| Concentration | 100ug/100ul |
| Storage Buffer | PBS, pH 7.4 with 0.02% sodium azide. |
| Storage Condition | This product is stable for several weeks at 4°C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20°C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt. |
| Formulation | Liquid |
| Species Reactivity | Human,Mouse,Rat |
| Specificity | ELISA titer: 1:20,000-1:80,000 Western blot analysis: 1:200-1:1,000 Optimal dilutions/concentrations should be determined by the end use |
| Purity | Affinity purified |
| Guarantee | abm guarantees that all our Anti-PPARD Antibody will perform as described on this product webpage, if this is not the case we will provide you with a one-time replacement at no extra cost. Documentation and explanation of experiment conducted will be required when submitting a claim for replacement. |
| Depositor | SaierBio |
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