Anti-NR3C1 Antibody
Cat. No.
Y058461
Unit
100 μl
Price
$152.00
Specifications
| Cat. No. | Y058461 |
| Name | Anti-NR3C1 Antibody |
| Clone | Polyclonal |
| Price | $152.00 |
| Unit | 100 μl |
| Category | Polyclonal Antibodies |
| Gene Name | NR3C1 |
| Alias | GR |
| Application | IHC |
| Application Info | Optimal dilutions to be determined by researchers |
| Raised In | Rabbit |
| Clonality | Polyclonal |
| Reactivity | Human |
| Description | This gene encodes glucocorticoid receptor, which can function both as a transcription factor that binds to glucocorticoid response elements in the promoters of glucocorticoid responsive genes to activate their transcription, and as a regulator of other transcription factors. This receptor is typically found in the cytoplasm, but upon ligand binding, is transported into the nucleus. It is involved in inflammatory responses, cellular proliferation, and differentiation in target tissues. Mutations in this gene are associated with generalized glucocorticoid resistance. Alternative splicing of this gene results in transcript variants encoding either the same or different isoforms. Additional isoforms resulting from the use of alternate in-frame translation initiation sites have also been described, and shown to be functional, displaying diverse cytoplasm-to-nucleus trafficking patterns and distinct transcriptional activities (PMID:15866175). [provided by RefSeq, Feb 2011] |
| Immunogen | Peptide |
| Isotype | IgG |
| Concentration | 100ug/100ul |
| Recommended Dilutions | Optimal dilutions to be determined by researchers |
| Storage Buffer | PBS, pH 7.4 with 0.02% Sodium Azide |
| Storage Condition | This product is stable for several weeks at 4°C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20°C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt. |
| Formulation | Liquid |
| Species Reactivity | Human |
| Specificity | Human |
| Purity | Affinity purified |
| Guarantee | abm guarantees that all our Anti-NR3C1 Antibody will perform as described on this product webpage, if this is not the case we will provide you with a one-time replacement at no extra cost. Documentation and explanation of experiment conducted will be required when submitting a claim for replacement. |
| Depositor | SaierBio |
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