Anti-Mouse superoxide dismutase (SOD1, 24-36) Antibody
Cat. No.
Y075051
Unit
100 μl
Price
$560.00
Specifications
| Cat. No. | Y075051 |
| Name | Anti-Mouse superoxide dismutase (SOD1, 24-36) Antibody |
| Price | $560.00 |
| Unit | 100 μl |
| Category | Polyclonal Antibodies |
| Gene Name | SOD1 |
| Alias | IPOA |
| Application | WB |
| Application Info | A dilution of 1:500 to 1:1000 is recommended for this application. The optimal dilution should be determined by the end user. |
| Raised In | Rabbit |
| Clonality | Polyclonal |
| Reactivity | Mouse,Rat |
| Description | FUNCTION: Destroys radicals which are normally produced within the cells and which are toxic to biological systems. CATALYTIC ACTIVITY: 2 superoxide + 2 H+ = O2 + H2O2. COFACTOR: Binds 1 copper ion per subunit. COFACTOR: Binds 1 zinc ion per subunit. SUBUNIT: Homodimer. SUBCELLULAR LOCATION: Cytoplasm. DISEASE: Defects in SOD1 are the cause of familial amyotrophic lateral sclerosis (FALS); also called amyotrophic lateral sclerosis 1 (ALS1 or ALS). ALS is a degenerative disorder of motorneurons in the cortex, brainstem and spinal cord. ALS is characterized by muscular weakness and atrophy beginning in the hands and spreading to the forearms and legs. Muscle fasciculations are commonly visible. Sensory abnormalities are absent. Death usually occurs within 2 to 5 years. ALS is sometimes referred to as Lou Gehrig disease after the famous American baseball player who was diagnosed with the disorder. FALS, the familial form of ALS, accounts for about 10% of the cases and is transmitted in an autosomal dominant manner. The mean age at onset of FALS is 45 years. MISCELLANEOUS: Zinc binding promotes dimerization. SIMILARITY: Belongs to the Cu-Zn superoxide dismutase family. |
| Immunogen | A synthetic peptide (ASGEPVV LSGQIT) as part of mouse superoxide dismutase (SOD1) protein (aa: 24-36) conjugated to diphtheria toxoid |
| Concentration | 1ug/ul |
| Recommended Dilutions | A dilution of 1:500 to 1:1000 is recommended for this application. The optimal dilution should be determined by the end user. |
| Storage Buffer | PBS, pH 7.4 with 0.02% sodium azide. |
| Storage Condition | This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20° C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt. |
| Formulation | Liquid |
| Species Reactivity | Mouse,Rat |
| Specificity | Specificity was confirmed by western blot detecting mouse superoxide dismutase (SOD1). |
| Purity | Filter purified |
| Guarantee | abm guarantees that all our Anti-Mouse superoxide dismutase (SOD1, 24-36) Antibody will perform as described on this product webpage, if this is not the case we will provide you with a one-time replacement at no extra cost. Documentation and explanation of experiment conducted will be required when submitting a claim for replacement. |
| Depositor | Biosensis |
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