Anti-MEK3 Antibody
Specifications
Cat. No. | Y058147 |
Name | Anti-MEK3 Antibody |
Clone | Polyclonal |
Price | $152.00 |
Unit | 100 μl |
Category | Polyclonal Antibodies |
Gene Name | MEK3 |
Application | WB,IHC,ELISA |
Application Info | For research use only Peptide ELISA titer: 1:20,000-80,000 Western blot analysis: 1:200-1000 Immunohistochemistry: 1:200-400 Optimal dilutions/concentrations should be determined by the end use. |
Raised In | Rabbit |
Clonality | Polyclonal |
Reactivity | Human,Mouse,Rat |
Description | The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase is activated by mitogenic and environmental stress, and participates in the MAP kinase-mediated signaling cascade. It phosphorylates and thus activates MAPK14/p38-MAPK. This kinase can be activated by insulin, and is necessary for the expression of glucose transporter. Expression of RAS oncogene is found to result in the accumulation of the active form of this kinase, which thus leads to the constitutive activation of MAPK14, and confers oncogenic transformation of primary cells. The inhibition of this kinase is involved in the pathogenesis of Yersina pseudotuberculosis. Multiple alternatively spliced transcript variants that encode distinct isoforms have been reported for this gene |
Immunogen | Synthetic peptide conjugated to KLH |
Isotype | Rabbit IgG |
Concentration | 100ug/100ul |
Recommended Dilutions | For research use only Peptide ELISA titer: 1:20,000-80,000 Western blot analysis: 1:200-1000 Immunohistochemistry: 1:200-400 Optimal dilutions/concentrations should be determined by the end use. |
Storage Buffer | PBS, pH 7.4 with 0.02% Sodium Azide |
Storage Condition | This product is stable for several weeks at 4°C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20°C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt. |
Formulation | Liquid |
Species Reactivity | Human,Mouse,Rat |
Specificity | Not yet tested in other species |
Purity | Affinity purified |
Guarantee | abm guarantees that all our Anti-MEK3 Antibody will perform as described on this product webpage, if this is not the case we will provide you with a one-time replacement at no extra cost. Documentation and explanation of experiment conducted will be required when submitting a claim for replacement. |
Depositor | SaierBio |
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