Anti-Androgen Receptor Antibody
Specifications
Cat. No. | Y058080 |
Name | Anti-Androgen Receptor Antibody |
Clone | Polyclonal |
Price | $152.00 |
Unit | 100 μl |
Category | Polyclonal Antibodies |
Gene Name | AR |
Alias | AIS, NR3C4, SMAX1, HUMARA |
Application | WB,ELISA |
Application Info | Recommended dilutions Peptide ELISA: 1:40,000 WB: 1/200 - 1/1000 Not yet tested in other applications. Optimal dilutions/concentrations should be determined by the end user |
Raised In | Rabbit |
Clonality | Polyclonal |
Reactivity | Human,Mouse |
Description | The androgen receptor gene is more than 90 kb long and codes for a protein that has 3 major functional domains: the N-terminal domain, DNA-binding domain, and androgen-binding domain. The protein functions as a steroid-hormone activated transcription factor. Upon binding the hormone ligand, the receptor dissociates from accessory proteins, translocates into the nucleus, dimerizes, and then stimulates transcription of androgen responsive genes. This gene contains 2 polymorphic trinucleotide repeat segments that encode polyglutamine and polyglycine tracts in the N-terminal transactivation domain of its protein. Expansion of the polyglutamine tract causes spinal bulbar muscular atrophy (Kennedy disease). Mutations in this gene are also associated with complete androgen insensitivity (CAIS). Two alternatively spliced variants encoding distinct isoforms have been described. |
Immunogen | Synthetic peptide conjugated to KLH |
Isotype | Rabbit IgG |
Concentration | 100ug/100ul |
Recommended Dilutions | Recommended dilutions Peptide ELISA: 1:40,000 WB: 1/200 - 1/1000 Not yet tested in other applications. Optimal dilutions/concentrations should be determined by the end user |
Storage Buffer | PBS, pH 7.4 with 0.02% Sodium Azide |
Storage Condition | This product is stable for several weeks at 4°C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20°C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt. |
Formulation | Liquid |
Species Reactivity | Human,Mouse |
Specificity | Androgen Receptor antibody detects endogenous levels of Androgen Receptor protein. Not tested with other proteins |
Purity | Purified |
Guarantee | abm guarantees that all our Anti-Androgen Receptor Antibody will perform as described on this product webpage, if this is not the case we will provide you with a one-time replacement at no extra cost. Documentation and explanation of experiment conducted will be required when submitting a claim for replacement. |
Depositor | SaierBio |
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