Anti-AKT1 Antibody
Cat. No.
Y058027
Unit
100 μl
Price
$152.00
Specifications
| Cat. No. | Y058027 |
| Name | Anti-AKT1 Antibody |
| Clone | Polyclonal |
| Price | $152.00 |
| Unit | 100 μl |
| Category | Polyclonal Antibodies |
| Gene Name | AKT1 |
| Alias | RAC, PKB, PRKBA, AKT |
| Application | WB,ELISA,ICC/IF |
| Application Info | Recommended dilutions Peptide ELISA: 1:32,000 WB: 1/500 - 1/1000 IF:1:50-100. Not yet tested in other applications. Optimal dilutions/concentrations should be determined by the end user |
| Raised In | Rabbit |
| Clonality | Polyclonal |
| Reactivity | Human,Mouse |
| Description | The serine-threonine protein kinase encoded by the AKT1 gene is catalytically inactive in serum-starved primary and immortalized fibroblasts. AKT1 and the related AKT2 are activated by platelet-derived growth factor. The activation is rapid and specific, and it is abrogated by mutations in the pleckstrin homology domain of AKT1. It was shown that the activation occurs through phosphatidylinositol 3-kinase. In the developing nervous system AKT is a critical mediator of growth factor-induced neuronal survival. Survival factors can suppress apoptosis in a transcription-independent manner by activating the serine/threonine kinase AKT1, which then phosphorylates and inactivates components of the apoptotic machinery. Multiple alternatively spliced transcript variants have been found for this gene. |
| Immunogen | Synthetic peptide conjugated to KLH |
| Isotype | Rabbit IgG |
| Concentration | 100ug/100ul |
| Recommended Dilutions | Recommended dilutions Peptide ELISA: 1:32,000 WB: 1/500 - 1/1000 IF:1:50-100. Not yet tested in other applications. Optimal dilutions/concentrations should be determined by the end user |
| Storage Buffer | PBS, pH 7.4 with 0.02% Sodium Azide |
| Storage Condition | This product is stable for several weeks at 4°C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20°C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt. |
| Formulation | Liquid |
| Species Reactivity | Human,Mouse |
| Specificity | AKT1 antibody detects endogenous levels of AKT1 protein. Not tested with other proteins |
| Purity | Protein A purified |
| Guarantee | abm guarantees that all our Anti-AKT1 Antibody will perform as described on this product webpage, if this is not the case we will provide you with a one-time replacement at no extra cost. Documentation and explanation of experiment conducted will be required when submitting a claim for replacement. |
| Depositor | SaierBio |
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