Anti-AKAP13 Antibody
Specifications
Cat. No. | Y058721 |
Name | Anti-AKAP13 Antibody |
Clone | Polyclonal |
Price | $152.00 |
Unit | 100 μg |
Category | Polyclonal Antibodies |
Gene Name | AKAP13 |
Alias | Ht31, BRX, AKAP-Lbc, c-lbc, PROTO-LB, HA-3, ARHGEF13 |
Application | WB,ELISA |
Application Info | For research use only ELISA titer: 1:20,000-1:80,000 Western blot analysis: 1:500-1:1,000 Optimal dilutions/concentrations should be determined by the end use |
Raised In | Rabbit |
Clonality | Polyclonal |
Reactivity | Human |
Description | The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms containing c-terminal dbl oncogene homology (DH) and pleckstrin homology (PH) domains. The DH domain is associated with guanine nucleotide exchange activation for the Rho/Rac family of small GTP binding proteins, resulting in the conversion of the inactive GTPase to the active form capable of transducing signals. The PH domain has multiple functions. Therefore, these isoforms function as scaffolding proteins to coordinate a Rho signaling pathway, function as protein kinase A-anchoring proteins and, in addition, enhance ligand-dependent activity of estrogen receptors alpha and beta. [provided by RefSeq, Jul 2012] |
Immunogen | Affinity purified |
Concentration | 100ug/100ul |
Recommended Dilutions | For research use only ELISA titer: 1:20,000-1:80,000 Western blot analysis: 1:500-1:1,000 Optimal dilutions/concentrations should be determined by the end use |
Storage Buffer | PBS, pH 7.4 with 0.02% Sodium Azide |
Storage Condition | This product is stable for several weeks at 4°C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20°C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt. |
Formulation | Liquid |
Species Reactivity | Human |
Purity | Affinity purified |
Guarantee | abm guarantees that all our Anti-AKAP13 Antibody will perform as described on this product webpage, if this is not the case we will provide you with a one-time replacement at no extra cost. Documentation and explanation of experiment conducted will be required when submitting a claim for replacement. |
Depositor | SaierBio |
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