Anti-AGER Antibody
Cat. No.
Y058663
Unit
100 μl
Price
$152.00
Specifications
| Cat. No. | Y058663 |
| Name | Anti-AGER Antibody |
| Clone | Polyclonal |
| Price | $152.00 |
| Unit | 100 μl |
| Category | Polyclonal Antibodies |
| Gene Name | AGER |
| Alias | RAGE |
| Application | WB,IHC,ELISA |
| Application Info | For research use only ELISA titer: 1:20,000-1:80,000 Western blot analysis: 1:1,000-1:2,000 Immunohistochemistry: 1:100-1:500 Optimal dilutions/concentrations should be determined by the end use |
| Raised In | Rabbit |
| Clonality | Polyclonal |
| Reactivity | Human |
| Description | Mediates interactions of advanced glycosylation end products (AGE). These are nonenzymatically glycosylated proteins which accumulate in vascular tissue in aging and at an accelerated rate in diabetes. Acts as a mediator of both acute and chronic vascular inflammation in conditions such as atherosclerosis and in particular as a complication of diabetes. AGE/RAGE signaling plays an important role in regulating the production/expression of TNF-alpha, oxidative stress, and endothelial dysfunction in type 2 diabetes. Interaction with S100A12 on endothelium, mononuclear phagocytes, and lymphocytes triggers cellular activation, with generation of key proinflammatory mediators. |
| Immunogen | Affinity purified |
| Concentration | 100ug/100ul |
| Recommended Dilutions | For research use only ELISA titer: 1:20,000-1:80,000 Western blot analysis: 1:1,000-1:2,000 Immunohistochemistry: 1:100-1:500 Optimal dilutions/concentrations should be determined by the end use |
| Storage Buffer | PBS, pH 7.4 with 0.02% Sodium Azide |
| Storage Condition | This product is stable for several weeks at 4°C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20°C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt. |
| Formulation | Liquid |
| Species Reactivity | Human |
| Purity | Affinity purified |
| Guarantee | abm guarantees that all our Anti-AGER Antibody will perform as described on this product webpage, if this is not the case we will provide you with a one-time replacement at no extra cost. Documentation and explanation of experiment conducted will be required when submitting a claim for replacement. |
| Depositor | SaierBio |
Protocols
There are no Protocols for this product yet!
Documents
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FAQs
| For a western blot where a band is seen for this protein? | |
|
The observed molecular weight is 45-50 KDa
|
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